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                                  Software: NeuronIQ Release v1.5.zip (Version 1.5, Updated Feb 15, 2010)

                                  Documents: User Manual.pdf

                                  Source Codes: please contact Jie Cheng ( JCheng@tmhs.org ) for source codes of NeuronIQ

                                  Test Images: ImageSet1.zip (no de-noising and interpolation required)

                                                         ImageSet2.zip (de-noising and interpolation are required before the processing)  

     

                                    


    This version of NeuronIQ (Version 1.5) can only run on a machine with Matlab installed. No installation is required for this software. Just downloaded the source codes and run the program under Matlab environment. Please read and agree the license before running the program.

    Sponsors:
    The Center for Bioengineering and Informatics, The Methodist Hospital Research Institute, Houston, Texas
    Harvard NeuroDiscovery Center, formally known as the HCNR (Harvard Center for Neurodegeneration and Repair), Harvard Medical School. Boston, Massachusetts.
    PI: Professor Stephen Wong

    Key Collaborators:
    Professor Bernardo Sabatini, M.D., Ph.D., Department of Neurobiology, Harvard Medical School. http://neuro.med.harvard.edu/faculty/sabatini.html

    We acknowledge the productive collaboration with Professor Bernardo Sabatini in the development of NeuronIQ and appreciate the valuable feedbacks on the earlier NeuronIQ prototype from his lab.

    References:

    1. J. Cheng, X. Zhou, E. Miller, R.M. Witt, J. Zhu, B.L.Sabatini and S.T. Wong, A novel computational approach for automatic dendrite spines detection in two-photon laser scan microscopy, Journal of Neuroscience Method, 165(1):122-134, Sept. 2007

    2. Wenjia Bai, Xiaobo Zhou, Liang Ji, Jie Cheng, Stephen T. C. Wong, Automatic dendritic spine analysis in two-photon laser scanning microscopy images, Cytometry, Volume 71A, Issue 10, Pages 818-826, Oct. 2007

     3. Y. Zhang, X. Zhou, R.M. Witt, B.L. Sabatini, D. Adjeroh and S.T. Wong, Dendritic spine detection using curvilinear structure detector and LDA classifier, NeuroImage, Vol. 36, Issue 2, Pages 346-360, June 2007

     

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