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This version of
NeuronIQ (Version 1.5) can only run on
a machine with Matlab installed. No installation is
required for this software. Just downloaded the
source codes and run the program under Matlab
environment. Please read and agree the license
before running the program.
Sponsors:
The Center for Bioengineering and Informatics, The
Methodist Hospital Research Institute, Houston,
Texas
Harvard NeuroDiscovery Center,
formally known as the HCNR
(Harvard Center for Neurodegeneration and
Repair), Harvard Medical School.
Boston, Massachusetts.
PI: Professor Stephen Wong
Key Collaborators:
Professor Bernardo Sabatini, M.D., Ph.D., Department
of Neurobiology, Harvard Medical School.
http://neuro.med.harvard.edu/faculty/sabatini.html
We acknowledge the productive collaboration with
Professor Bernardo Sabatini in the development of
NeuronIQ and appreciate the valuable feedbacks on
the earlier NeuronIQ prototype from his lab.
References:
1. J. Cheng, X. Zhou, E. Miller, R.M. Witt, J. Zhu,
B.L.Sabatini and S.T. Wong, A novel computational
approach for automatic dendrite spines detection in
two-photon laser scan microscopy, Journal of
Neuroscience Method, 165(1):122-134, Sept. 2007
2. Wenjia Bai, Xiaobo Zhou, Liang Ji, Jie Cheng,
Stephen T. C. Wong, Automatic dendritic spine
analysis in two-photon laser scanning microscopy
images, Cytometry, Volume 71A, Issue 10, Pages
818-826, Oct. 2007
3. Y. Zhang, X. Zhou, R.M. Witt, B.L. Sabatini, D.
Adjeroh and S.T. Wong, Dendritic spine detection
using curvilinear structure detector and LDA
classifier, NeuroImage, Vol. 36, Issue 2, Pages 346-360, June 2007 |
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Downloading NeuronIQ TE (Version 2.0):
Software:
NeuronIQ TE2.0.rar (Version 2.0, Updated Nov 23, 2011)
Documents: User Manual.pdf
Test Images: ImageSet.rar
NeuronIQ TE2.0 runs on a Windows 32-bit system. Please follow the manual to install the software. For running three-dimensional display smoothly, it is suggested a high-end graphic card is installed. Please read and agree the license before running the software.
Sponsors:
Biomedical Image Computing Lab, Department of Systems Medicine and Bioengineering, The Methodist Hospital Research Institute, Houston, Texas
PI: Professor Stephen Wong
Key Collaborators:
Dr. Yong Kim, M.D., Ph.D., Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, NY.
http://lab.rockefeller.edu/greengard/contact
We acknowledge the productive collaboration with Dr. Yong Kim in the development of NeuronIQ and appreciate the valuable feedbacks on the earlier NeuronIQ prototype from the Greengard lab.
References:
1. T. He, Z. Xue, S.T. Wong. A novel approach for three dimensional dendrite spine segmentation and classification. SPIE Medical Imaging 2012, Image Processing, Feb. 2012.
2. Li Q, Deng Z, Zhang Y, Zhou X, Nagerl V, Wong ST., A Global Spatial Similarity Optimization Scheme to Track Large Numbers of Dendritic Spines in Time-lapse Confocal Microscopy. IEEE Trans Med Imaging. 2011 Mar, 30(3):632-41.
3. Zhang Y, Chen K, Baron M, Teylan MA, Kim Y, Song Z, Greengard P, Wong ST., A Neurocomputational Method for Fully Automated 3D Dendritic Spine Detection and Segmentation of Medium-sized Spiny Neurons, NeuroImage, 50 (2010) 1472–1484 [PMID: 20100579]
4. Peng Shi, Xiaobo Zhou, Marta Lipinski, Alexei Degretev, and Stephen TC Wong., An Integrative High Content Analysis Pipeline for Alzheimer’s Disease Drug Discovery, 18th Annual International Conference on Intelligent Systems for Molecular Biology (ISMB’10), Boston, Jul 11-Jul 13, 2010.
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