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Downloading ZFIQ

This version of CBI_Platform( Version 1.0) can only be installed on a windows machine, and the OS should be Windows 2000 or later. To install CBI_Platform, you need to download it first, CBI_Platform is easy to install, like most windows software you have seen. Please read and agree the license before installation.

Note: Reboot is needed to make the installation complete.

PI:
Stephen Wong
Project Manager:
: Zhong Xue, PhD
Developers: Gang Li, Tianming Liu, Jingxin Nie, Yong Zhang
Algorithms and pipeline construction: Gang Li, Jingxin Nie 
Documentation: Tianming Liu, Jingxin Nie, Kaiming Li, Dagem Mammo, Stephen Wong
Other contributors: Hai Li, Xintao Hu, Fei Qin, Haifeng Zhao, Hui Yan, Lei Guo, Jianfeng Lu, Ling Huang
Sponsors:
The Center for Bioengineering and Informatics, The Methodist Hospital Research Institute, Houston, Texas
Harvard NeuroDiscovery Center(Formally known as Harvard Center for Neurodegeneration and Repair), Harvard Medical School, Boston, Massachusetts.
PI: Professor Stephen Wong

Key Collaborators:
Biological:

Dr. Weiming Xia, Department of Neurology, Harvard Medical School. http://xialab.bwh.harvard.edu/staff/wxia/
Dr. Jarema Malicki, Department of Ophthalmology, Massachusetts Eye & Ear Infirmary, Harvard Medical School. http://www.howelaboratory.harvard.edu/malicki.htm
Dr. Scott Holley, Department of Molecular, Cellular and Developmental Biology, Yale University.        http://www.biology.yale.edu/facultystaff/holley.html

Technical:
Dr. Lei Guo, School of Automation, Northwestern Polytechnical University, Xian, PR China.
Dr. Jianfeng Lu, Department of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, PR China

References:  
1. Tianming Liu. A quantitative zebrafish phenotyping tool for developmental biology and disease modeling. IEEE Signal and Processing Magazine. 24(1):126-129. 2007

2. Li G, Liu T, Tarokh A, Nie J, Guo L, Mara A, Holley S, Wong ST. 3D cell nuclei segmentation based on gradient flow tracking.BMC Cell Biol. 2007 Sep 4;8:40.

3. Li G, Liu T, Nie J, Guo L, Malicki J, Mara A, Holley SA, Xia W, Wong ST. Detection of Blob Objects in Microscopic Zebrafish Images Based on Gradient Vector Diffusion. Cytometry A. 2007 Oct;71(10):835-45. Cytometry A, 2007.

4. Li G, Liu T, Nie J, Guo L, Chen J, Zhu J, Xia W, Mara A, Holley S, Wong ST. Segmentation of touching cell nuclei using gradient flow tracking. J Microsc. 2008 Jul;231(Pt 1):47-58.

5. Tianming Liu, J Lu, Y Wang, William A Campbell, Ling Huang, J Zhu, Weiming Xia, Stephen Wong. Computerized Image Analysis for Quantitative Neuronal Phenotyping in Zebrafish. Journal of Neuroscience Methods. 153(2):190-202. 2006.

6. William A. Campbell, Henrik Zetterberg, Stephanie Baulac, Tianming Liu, Stephen T. C. Wong, Tao Zhong, Weiming Xia. Zebrafish lacking Alzheimer presenilin enhancer 2 (Pen-2) demonstrate excessive p53-dependent apoptosis and neuronal loss. Journal of Neurochemistry. 96:1423-40. 2006.

7.Tianming Liu, Gang Li, Jingxin Nie, Ashley Tarokh, Xiaobo Zhou, Lei Guo, Jarema Malicki, Weiming Xia. An Automated Cell Detection Method for Quantitative  Neuronal Cell Fate Determination in Zebrafish. Neuroinformatics, accepted for publish, 2007.